Ontology highlight
ABSTRACT:
SUBMITTER: Ye CY
PROVIDER: S-EPMC5680721 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
RNA biology 20161014 8
Circular RNAs (circRNAs) have been identified in diverse eukaryotic species and are characterized by RNA backsplicing events. Current available methods for circRNA identification are able to determine the start and end locations of circRNAs in the genome but not their full-length sequences. In this study, we developed a method to assemble the full-length sequences of circRNAs using the backsplicing RNA-Seq reads and their corresponding paired-end reads. By applying the method to an rRNA-depleted ...[more]