Drug abusers have impaired cerebral oxygenation and cognition during exercise.

ABSTRACT:

Background

Individuals with Substance Use Disorder (SUD) have lower baseline metabolic activity of the prefrontal cortex (PFC) associated with impairment of cognitive functions in decision-making and inhibitory control. Aerobic exercise has shown to improve PFC function and cognitive performance, however, its effects on SUD individuals remain unclear.

Purpose

To verify the cognitive performance and oxygenation of the PFC during an incremental exercise in SUD individuals.

Methods

Fourteen individuals under SUD treatment performed a maximum graded exercise test on a cycle ergometer with continuous measurements of oxygen consumption, PFC oxygenation, and inhibitory control (Stroop test) every two minutes of exercise at different intensities. Fifteen non-SUD individuals p

SUBMITTER: Grandjean da Costa K 

PROVIDER: S-EPMC5681256 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature