Patterns and Predictors of Frailty Transitions in Older Men: The Osteoporotic Fractures in Men Study.

ABSTRACT:

Objectives

To describe the natural history of frailty transitions in a large cohort of community-dwelling older men and identify predictors associated with progression to or improvement from states of greater frailty.

Design

Prospective cohort study.

Setting

Six U.S. sites.

Participants

Community-dwelling men aged 65 and older (N = 5,086).

Measurements

Frailty was measured at baseline and an average of 4.6 years later. Frailty was defined as having three or more of the following components (low lean mass, weakness, self-reported exhaustion, low activity level, and slow walking speed); prefrailty was defined as having one or two components. Separate multivariable logistic regression models were analyzed for progression and improvement in frailty status.

SUBMITTER: Pollack LR 

PROVIDER: S-EPMC5681371 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature