More Than Gliding: Involvement of GldD and GldG in the Virulence of Flavobacterium psychrophilum.

ABSTRACT: A fascinating characteristic of most members of the genus Flavobacterium is their ability to move over surfaces by gliding motility. Flavobacterium psychrophilum, an important pathogen of farmed salmonids worldwide, contains in its genome the 19 gld and spr genes shown to be required for gliding or spreading in Flavobacterium johnsoniae; however, their relative role in its lifestyle remains unknown. In order to address this issue, two spreading deficient mutants were produced as part of a Tn4351 mutant library in F. psychrophilum strain THCO2-90. The transposons were inserted in gldD and gldG genes. While the wild-type strain is proficient in adhesion, biofilm formation and displays strong proteolytic activity, both mutants los

SUBMITTER: Perez-Pascual D 

PROVIDER: S-EPMC5682007 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature