Comparative clinical effectiveness and cost effectiveness of endovascular strategy <i>v</i> open repair for ruptured abdominal aortic aneurysm: three year results of the IMPROVE randomised trial.

ABSTRACT: Objective To assess the three year clinical outcomes and cost effectiveness of a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair for patients with suspected ruptured abdominal aortic aneurysm.Design Randomised controlled trial.Setting 30 vascular centres (29 in UK, one in Canada), 2009-16.Participants 613 eligible patients (480 men) with a clinical diagnosis of ruptured aneurysm, of whom 502 underwent emergency repair for rupture.Interventions 316 patients were randomised to an endovascular strategy (275 with confirmed rupture) and 297 to open repair (261 with confirmed rupture).Main outcome measures Mortality, with reinterventions after aneurysm repair, quality of life, and hospital costs t

SUBMITTER: IMPROVE Trial Investigators 

PROVIDER: S-EPMC5682594 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature