Potential Risk for Localized Aggressive Periodontitis in African American Preadolescent Children.

ABSTRACT:

Purpose

This study aimed to evaluate the potential risk for localized aggressive periodontitis (LAgP) in African American children by detection of the potential periodontal pathogen Aggregatibacter actinomycetemcomitans (Aa) using polymerase chain reaction (PCR) and microbiome analysis.

Methods

Twenty-one pre-adolescents (age range equals 10.7 to 13.1 years old) were recruited, for this IRB-approved study. Oral examination included limited periodontal examination determining bleeding index (BOP) and periodontal probing (PD). An oral mucosa sample was used for analysis.

Results

Nine of 21 children were Aa+ by PCR. The Aa+ group had a significantly higher proportion of teeth with BOP and PD greater than four mm than the Aa- group (P=0.014 and 0.006 for percent BOP and p

SUBMITTER: Childers NK 

PROVIDER: S-EPMC5682943 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature