Triangulation of language-cognitive impairments, naming errors and their neural bases post-stroke.

ABSTRACT: In order to gain a better understanding of aphasia one must consider the complex combinations of language impairments along with the pattern of paraphasias. Despite the fact that both deficits and paraphasias feature in diagnostic criteria, most research has focused only on the lesion correlates of language deficits, with minimal attention on the pattern of patients' paraphasias. In this study, we used a data-driven approach (principal component analysis - PCA) to fuse patient impairments and their pattern of errors into one unified model of chronic post-stroke aphasia. This model was subsequently mapped onto the patients' lesion profiles to generate the triangulation of language-cognitive impairments, naming errors and their neural correlates. Specifically, we established the pattern of c

SUBMITTER: Halai AD 

PROVIDER: S-EPMC5683039 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature