Characterization of skin function associated with obesity and specific correlation to local/systemic parameters in American women.

ABSTRACT:

Background

Obesity is considered problematic not only as a major cause of diabetes, hypertension, and dyslipidemia, but also as a risk of intractable dermatosis; however influence of obesity on skin function has not been clarified. To clarify the mechanism of obesity-associated skin disorders, we aimed to characterize the skin function of subjects with obesity, and identify possible influencing factors.

Methods

Complex analyses including instrumental measurement, biochemical and lipidomics were performed for facial skin and physical evaluation in 93 Caucasian women with obesity (OB) and non-obesity (NOB).

Results

In OB, imbalance in metabolism of carbohydrate and lipid, autonomic nerve activity, and secreted factors were confirmed. In the skin properties in OB, surfac

SUBMITTER: Mori S 

PROVIDER: S-EPMC5683228 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature