Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungus Malbranchea cinnamomea.

ABSTRACT:

Background

Genome and transcriptome sequencing has greatly facilitated the understanding of biomass-degrading mechanisms in a number of fungal species. The information obtained enables the investigation and discovery of genes encoding proteins involved in plant cell wall degradation, which are crucial for saccharification of lignocellulosic biomass in second-generation biorefinery applications. The thermophilic fungus Malbranchea cinnamomea is an efficient producer of many industrially relevant enzymes and a detailed analysis of its genomic content will considerably enhance our understanding of its lignocellulolytic system and promote the discovery of novel proteins.

Results

The 25-million-base-pair genome of M. cinnamomea FCH 10.5 was sequenced with 225× cover

SUBMITTER: Huttner S 

PROVIDER: S-EPMC5683368 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature