Chronic prostatitis and comorbid non-urological overlapping pain conditions: A co-twin control study.

ABSTRACT:

Objectives

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by pain and voiding symptoms in the absence of an obvious infection or other cause. CP/CPPS frequently occurs with non-urological chronic overlapping pain conditions (COPCs) of unknown etiology. We conducted a co-twin control study in men discordant for chronic prostatitis (CP), an overarching diagnosis of which approximately 90% is CP/CPPS. The primary aim was to investigate the contribution of familial factors, including shared genetic and common environmental factors, to the comorbidity of CP and COPCs.

Methods

Data from 6824 male twins in the Vietnam Era Twin Registry were examined to evaluate the association between self-reported lifetime physician diagnosis of CP with COPCs including

SUBMITTER: Gasperi M 

PROVIDER: S-EPMC5683425 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature