Phylodynamic applications in 21^st century global infectious disease research.

ABSTRACT:

Background

Phylodynamics, the study of the interaction between epidemiological and pathogen evolutionary processes within and among populations, was originally defined in the context of rapidly evolving viruses and used to characterize transmission dynamics. The concept of phylodynamics has evolved since the early 21^st century, extending its reach to slower-evolving pathogens, including bacteria and fungi, and to the identification of influential factors in disease spread and pathogen population dynamics.

Results

The phylodynamic approach has now become a fundamental building block for the development of comparative phylogenetic tools capable of incorporating epidemiological surveillance data with molecular sequences into a single statistical framework. These inno

SUBMITTER: Rife BD 

PROVIDER: S-EPMC5683535 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature