Comparative study of the 7th and 8th AJCC editions for gastric cancer patients after curative surgery.

ABSTRACT:

Objectives

The classification of pathological tumor-node-metastasis (pTNM) staging of gastric cancer was revised in the 8th American Joint Committee on Cancer (AJCC) edition. The major revision was the separation of pN3a and pN3b in the pTNM staging. The current study evaluated the prognostic impact of this change.

Methods

A total of 1,517 patients who underwent curative surgery for gastric cancer with a retrieved lymph node number ≥15 at our institution from January 1995 to December 2011 were enrolled. Survival was compared for the disease classified according to both the 7th and 8th editions.

Results

After separation of pN3a and pN3b in the pTNM stage definition, the 8th edition still provides significant survival differences between each stage. The multivariate ana

SUBMITTER: Fang WL 

PROVIDER: S-EPMC5683565 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature