Invasive Aspergillus terreus morphological transitions and immunoadaptations mediating antifungal resistance.

ABSTRACT:

Background and aims

Aspergillus terreus Thom is a pathogen of public health and agricultural importance for its seamless abilities to expand its ecological niche. The aim of this study was holistically to investigate A. terreus morphological and immunoadaptations and their implication in antifungal resistance and proliferation during infection.

Materials and methods

In-depth unstructured mining of relevant peer-reviewed literature was performed for A. terreus morphological, immune, resistance, and genetic diversity based on the sequenced calmodulin-like gene.

Results

Accessory conidia and phialidic conidia produced by A. terreus confer discrete anti-fungal resistance that ensures survivability during therapies. Interestingly, by producing u

SUBMITTER: Bengyella L 

PROVIDER: S-EPMC5683776 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature