Potentially Harmful Medication Use and Decline in Health-Related Quality of Life among Community-Dwelling Older Adults.

ABSTRACT:

Background

Several scales to quantify the impact of potentially harmful medications (PHMs) have been shown to predict mortality and functional decline; however, the effect of PHMs on quality of life (QoL) has not been well-studied.

Objective

The aims of this study were to investigate an association between PHM use and change in health-related QoL among community-dwelling older adults, and to compare the predictive capacity of PHM scales.

Methods

We conducted a retrospective cohort study using prescription claims data and survey responses. A total of 426 community-dwelling adults aged 65 years or older who visited senior centers and had received prescriptions through a statewide prescription drug subsidy program were included. Anticholinergic Cognitive Burden (ACB), Dr

SUBMITTER: Ie K 

PROVIDER: S-EPMC5684052 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature