Reduced kidney function is associated with BMD, bone loss and markers of mineral homeostasis in older women: a 10-year longitudinal study.

ABSTRACT: Kidney function decreases with age; however, the long-term influence on bone density (BMD) in older women already at risk of osteoporosis is unknown. We followed kidney function and bone loss for 10 years. Declining kidney function was adversely associated with bone loss and mineral homeostasis in old women, though it attenuated with advanced aging.

Introduction

Existing studies do not fully address the relationship between kidney function and bone metabolism with advanced aging in Caucasian women. This study describes the association between kidney function, BMD, bone loss and bone metabolism in older women and provides a review of the available literature for context.

Methods

We studied participants from the OPRA cohort with follow-up after 5 and 10 years. Using plasma cyst

SUBMITTER: Malmgren L 

PROVIDER: S-EPMC5684332 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature