Canonical germinant receptor is dispensable for spore germination in Clostridium botulinum group II strain NCTC 11219.

ABSTRACT: Clostridium botulinum is an anaerobic sporeforming bacterium that is notorious for producing a potent neurotoxin. Spores of C. botulinum can survive mild food processing treatments and subsequently germinate, multiply, produce toxin and cause botulism. Control of spore germination and outgrowth is therefore essential for the safety of mildly processed foods. However, little is known about the process of spore germination in group II C. botulinum (gIICb), which are a major concern in chilled foods because they are psychrotrophic. The classical model of spore germination states that germination is triggered by the binding of a germinant molecule to a cognate germinant receptor. Remarkably, unlike many other sporeformers, gIICb has only one predicted canonical germinant receptor although it r

SUBMITTER: Clauwers C 

PROVIDER: S-EPMC5684421 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature