Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units.

ABSTRACT:

Background

Delirium is a primary adverse event in ventilated patients who receive long-term monosedative treatment. Sequential sedation may reduce these adverse effects. This study evaluated risk factors for delirium in sequential sedation patients.

Methods

A total of 141 patients who underwent sequential sedation were enrolled. Delirium was diagnosed using Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) scale. Univariate and multivariate Cox proportional hazards regressions were used to predict risk factors.

Results

Older age (≥51) (RR = 2.432, 95% CL 1.316-4.494, p = 0.005), higher SOFA score (≥14) (RR = 2.022, 95% CL 1.076-3.798, p = 0.029), regular smoking (RR = 2.366, 95% CL 1.277-4.382, p = 0.006), and higher maintenance do

SUBMITTER: Yang J 

PROVIDER: S-EPMC5684530 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature