Metabolic Differences between Dogs of Different Body Sizes.

ABSTRACT:

Introduction

The domesticated dog, Canis lupus familiaris, has been selectively bred to produce extreme diversity in phenotype and genotype. Dogs have an immense diversity in weight and height. Specific differences in metabolism have not been characterized in small dogs as compared to larger dogs.

Objectives

This study aims to identify metabolic, clinical, and microbiota differences between small and larger dogs.

Methods

Gas chromatography/mass spectrometry, liquid chromatography/tandem mass spectrometry, clinical chemistry analysis, dual-energy X-ray absorptiometry, and 16S pyrosequencing were used to characterize blood metabolic, clinical, and fecal microbiome systems, respectively. Eighty-three canines from seven different breeds, fed the same kibble diet fo

SUBMITTER: Middleton RP 

PROVIDER: S-EPMC5684564 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature