A study on the expression of apoptotic molecules related to death receptor and endoplasmic reticulum pathways in the jejunum of AFB₁-intoxicated chickens.

ABSTRACT: Aflatoxin B₁ (AFB₁) is a common contaminant of poultry feeds in tropical and subtropical climates. Early researches have well established the hepatotoxic, carcinogenic, and immunotoxic effects of AFB₁ on humans and animals. Recently, it has been shown that AFB₁ could cause the up- or down-alteration of mitochondrial pathway molecule expression. However, the information on the expression of death receptor and endoplasmic reticulum molecules in the jejunal apoptosis induced by AFB₁ were unavailable. So the present study was conducted to explore the expression of apoptotic molecules related to death receptor and endoplasmic reticulum in the jejunal cells of chickens exposed to AFB₁ diet for 3 weeks. Total of 144 one-day-old chi

SUBMITTER: Zheng Z 

PROVIDER: S-EPMC5685699 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature