Amino acid catabolism-directed biofuel production in Clostridium sticklandii: An insight into model-driven systems engineering.

ABSTRACT: Model-driven systems engineering has been more fascinating process for the microbial production of biofuel and bio-refineries in chemical and pharmaceutical industries. Genome-scale modeling and simulations have been guided for metabolic engineering of Clostridium species for the production of organic solvents and organic acids. Among them, Clostridium sticklandii is one of the potential organisms to be exploited as a microbial cell factory for biofuel production. It is a hyper-ammonia producing bacterium and is able to catabolize amino acids as important carbon and energy sources via Stickland reactions and the development of the specific pathways. Current genomic and metabolic aspects of this bacterium are comprehensively reviewed herein, which provided information for learning about pro

SUBMITTER: Sangavai C 

PROVIDER: S-EPMC5686429 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature