Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups.

ABSTRACT: There are twenty-five published structures of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (Mtb-AnPRT) that use the same crystallization protocol. The structures include protein complexed with natural and alternative substrates, protein:inhibitor complexes, and variants with mutations of substrate-binding residues. Amongst these are varying space groups (i.e. P2₁, C2, P2₁2₁2, P2₁2₁2₁). This article outlines experimental details for 3 additional Mtb-AnPRT:inhibitor structures. For one protein:inhibitor complex, two datasets are presented - one generated by crystallization of protein in the presence of the inhibitor and another where a protein crystal was so

SUBMITTER: Evans GL 

PROVIDER: S-EPMC5686470 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature