The Use of Resveratrol as an Adjuvant Treatment of Pain in Endometriosis: A Randomized Clinical Trial.

ABSTRACT:

Context

Resveratrol has been used for the treatment of endometriosis.

Objective

To compare resveratrol (40 mg/d) with monophasic contraceptive pill (COC) to COC with placebo for the reduction of pain scores.

Design

A randomized clinical trial.

Setting

University Hospital.

Patients

Women (ages 20 to 50) with laparoscopic diagnosis of endometriosis were eligible for the study. Exclusion criteria: pregnancy, allergy to resveratrol, or contraindications to COC, use of agonists of gonadotropin release hormone or danazol in the last month, or had used depot medroxyprogesterone acetate or Mirena®.

Intervention

Subjects were randomized using a computer-generated randomization list to receive COC for 42 days to be taken with identical capsules containing 4

SUBMITTER: Mendes da Silva D 

PROVIDER: S-EPMC5686687 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature