Varicella zoster virus-associated morbidity and mortality in Africa - a systematic review.

ABSTRACT:

Background

Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV epidemiology are from industrialised temperate countries and cannot be used to guide decisions on the immunization policy against VZV in Africa. This systematic review aims to review the published data on VZV morbidity and mortality in Africa.

Methods

All published studies conducted in Africa from 1974 to 2015 were eligible. Eligible studies must have reported any VZV epidemiological measure (incidence, prevalence, hospitalization rate and mortality rate). For inclusion in the review, studies must have used a defined VZV case definition, be it clinical or laboratory-based.

Results

Twenty articles from 13 African

SUBMITTER: Hussey H 

PROVIDER: S-EPMC5686819 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature