Dual wavelength stimulation of polymeric nanoparticles for photothermal therapy.

ABSTRACT:

Background and objective

Photothermal therapy (PTT) has several applications in the areas of wound healing, pain management, bacterial infection control, and cancer treatment dependent on the temperature that is generated. PTT is often used exclusively with near infrared (NIR) light and most nanoparticles (NP) used for PTT are designed to absorb within one narrow range of wavelengths. We have developed a dual-wavelength photothermal therapy by capitalizing on the dual absorption of nanoparticles in the blue and NIR range.

Materials and methods

Our lab has previously developed NP based on the semiconducting, conjugated polymer poly[4,4-bis(2-ethylhexyl)-cyclopenta[2,1-b;3,4-b']dithiophene-2,6-diyl-alt-2,1,3-benzoselenadiazole-4,7-diyl] (PCPDTBSe). The NP have strong absorptio

SUBMITTER: Kelkar SS 

PROVIDER: S-EPMC5687087 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature