Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-guided Photodynamic Cancer Therapy.

ABSTRACT: Noninvasive dynamic positron emission tomography (PET) imaging was used to investigate the balance between renal clearance and tumor uptake behaviors of polyethylene glycol (PEG)-modified porphyrin nanoparticles (TCPP-PEG) with various molecular weights. TCPP-PEG_10K nanoparticles with clearance behavior would be a good candidate for PET image-guided photodynamic therapy.

SUBMITTER: Cheng L 

PROVIDER: S-EPMC5687274 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature