A Novel Medium for Enhancing Callus Growth of Hazel (Corylus avellana L.).

ABSTRACT: Paclitaxel is a powerful antimitotic agent with excellent activity against a range of cancers. Hazel has been described as a paclitaxel-producing species among angiosperms. Fast-growing callus is a prerequisite for the success of callus production and then paclitaxel production. Therefore, optimizing the medium culture for enhancing callus growth is a crucial step for paclitaxel production. In this research, Murashige and Skoog (1962) (MS) medium was optimized for improving callus growth of hazel (Corylus avellana L.). The M₁₀ medium (MS medium with pH 6.0 and supplemented with 1000 mg l^-1 spirulina powder, 1000 mg l^-1 casein hydrolysate and 3 g l^-1 gelrite) significantly improved hazel callus growth. This modified MS medium increased callus fres

SUBMITTER: Salehi M 

PROVIDER: S-EPMC5688170 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature