The Gene Ontology of eukaryotic cilia and flagella.

ABSTRACT:

Background

Recent research into ciliary structure and function provides important insights into inherited diseases termed ciliopathies and other cilia-related disorders. This wealth of knowledge needs to be translated into a computational representation to be fully exploitable by the research community. To this end, members of the Gene Ontology (GO) and SYSCILIA Consortia have worked together to improve representation of ciliary substructures and processes in GO.

Methods

Members of the SYSCILIA and Gene Ontology Consortia suggested additions and changes to GO, to reflect new knowledge in the field. The project initially aimed to improve coverage of ciliary parts, and was then broadened to cilia-related biological processes. Discussions were documented in a public tracker. We

SUBMITTER: Roncaglia P 

PROVIDER: S-EPMC5688719 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature