Pharmacological potential of Bidens pilosa L. and determination of bioactive compounds using UHPLC-QqQ_LIT-MS/MS and GC/MS.

ABSTRACT:

Background

Research of natural products from traditionally used medicinal plants to fight against the human ailments is fetching attention of researchers worldwide. Bidens pilosa Linn. var. Radiata (Asteraceae) is well known for its folkloric medicinal use against various diseases from many decades. Mizoram, North East India, has high plant diversity and the use of this plant as herbal medicine is deep rooted in the local tribes. The present study was executed to understand the pharmacological potential of B. pilosa leaves extract.

Methods

The antimicrobial potential was determined using agar well diffusion and broth microdilution method against bacterial and yeast pathogens. Cytotoxicity was evaluated using MTT and apoptotic DNA fragmentation assays. Further, the antioxidan

SUBMITTER: Singh G 

PROVIDER: S-EPMC5689161 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature