Bet v 1-like pollen allergens of multiple Fagales species can sensitize atopic individuals.

ABSTRACT:

Background

In the temperate climate zone of the Northern hemisphere, Fagales pollen allergy represents the main cause of winter/spring pollinosis. Among Fagales trees, pollen allergies are strongly associated within the Betulaceae and the Fagaceae families. It is widely accepted that Fagales pollen allergies are initiated by sensitization against Bet v 1, the birch pollen major allergen, although evidence is accumulating that the allergenic activity of some Bet v 1-like molecules has been underestimated.

Objective

To investigate the allergenic potential of the clinically most important Fagales pollen allergens from birch, alder, hazel, hornbeam, hop-hornbeam, oak, beech and chestnut.

Methods

To obtain the full spectrum of allergens, the three previously unavailable me

SUBMITTER: Hauser M 

PROVIDER: S-EPMC5689382 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature