Sleep Apnea and Cardiovascular Disease: Lessons From Recent Trials and Need for Team Science.

ABSTRACT: Emerging research highlights the complex interrelationships between sleep-disordered breathing and cardiovascular disease, presenting clinical and research opportunities as well as challenges. Patients presenting to cardiology clinics have a high prevalence of obstructive and central sleep apnea associated with Cheyne-Stokes respiration. Multiple mechanisms have been identified by which sleep disturbances adversely affect cardiovascular structure and function. Epidemiological research indicates that obstructive sleep apnea is associated with increases in the incidence and progression of coronary heart disease, heart failure, stroke, and atrial fibrillation. Central sleep apnea associated with Cheyne-Stokes respiration predicts incident heart failure and atrial fibrillation; among patients

SUBMITTER: Drager LF 

PROVIDER: S-EPMC5689452 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature