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Measurement-guided volumetric dose reconstruction for helical tomotherapy.


ABSTRACT: It was previously demonstrated that dose delivered by a conventional linear accelerator using IMRT or VMAT can be reconstructed - on patient or phantom datasets - using helical diode array measurements and a technique called planned dose perturbation (PDP). This allows meaningful and intuitive analysis of the agreement between the planned and delivered dose, including direct comparison of the dose-volume histograms. While conceptually similar to modulated arc techniques, helical tomotherapy introduces significant challenges to the PDP formalism, arising primarily from TomoTherapy delivery dynamics. The temporal characteristics of the delivery are of the same order or shorter than the dosimeter's update interval (50 ms). Additionally, the prevalence of often small and complex segments, part

SUBMITTER: Stambaugh C 

PROVIDER: S-EPMC5690083 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature

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