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Primary leiomyosarcoma of the bone: a case report and a review of the literature.


ABSTRACT:

Rationale

Leiomyosarcoma (LMS) is a malignant sarcoma that can occur in different anatomic sites, including the bone, showing similar histological characteristics but heterogeneous clinical behavior and prognosis. Primary bone LMS was first described in 1965. It is a very rare sarcoma, accounting for <0.7% of all primary malignant bone tumors.

Patient concerns

We report the case of a 52-year-old male with primary bone LMS who presented with a solitary osteolytic lesion with focal cortical destruction in the left clavicle, seen on an x-ray and subsequent computed tomography (CT) scan.

Diagnosis

The multidisciplinary Osteoncology team of our institute planned a biopsy that revealed the presence of spindle and pleomorphic cells with a positive reaction for smooth muscle

SUBMITTER: Recine F 

PROVIDER: S-EPMC5690758 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature