Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:H^- Isolates from Czech Patients with Novel Plasmid Composition Not Previously Seen in German Isolates.

ABSTRACT: Sorbitol-fermenting (SF) enterohemorrhagic Escherichia coli (EHEC) O157:H^- strains, first identified in Germany, have emerged as important pathogens throughout Europe. Besides chromosomally encoded Shiga toxin 2a (the major virulence factor), several putative virulence loci, including the hly, etp, and sfp operons, encoding EHEC hemolysin, type II secretion system proteins, and Sfp fimbriae, respectively, are located on the 121-kb plasmid pSFO157 in German strains. Here we report novel SF EHEC O157:H^- strains isolated from patients in the Czech Republic. These strains share the core genomes and chromosomal virulence loci encoding toxins (stx_2a and the cdtV-ABC operon) and adhesins (eae-γ, efa1, lpfA

SUBMITTER: Bauwens A 

PROVIDER: S-EPMC5691429 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature