Cystatin B, cathepsin L and D related to surrogate markers for cardiovascular disease in children.

ABSTRACT:

Objective

This study investigated potential associations between novel biomarkers for cardiovascular disease and other surrogate markers for health.

Methods

Community sample of 170 (92 boys and 78 girls) children aged 8-11 years. Total fat mass (TBF) and abdominal fat (AFM) were measured by Dual-energy x-ray absorptiometry (DXA). Total body fat was also expressed as percentage of total body mass (BF%), and body fat distribution was calculated as AFM/TBF. Maximal oxygen uptake (VO2PEAK), systolic and diastolic blood pressure (SBP and DBP) and pulse pressure (PP) were measured. Echocardiography was performed. Left atrial size (LA) and left ventricular mass (LVM) were measured. A follow-up DXA scan was available in 152 children (84 boys and 68 girls). Frozen serum samples were

SUBMITTER: Dencker M 

PROVIDER: S-EPMC5693439 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature