Phylogeographic separation and formation of sexually discrete lineages in a global population of Yersinia pseudotuberculosis.

ABSTRACT: Yersinia pseudotuberculosis is a Gram-negative intestinal pathogen of humans and has been responsible for several nationwide gastrointestinal outbreaks. Large-scale population genomic studies have been performed on the other human pathogenic species of the genus Yersinia, Yersinia pestis and Yersinia enterocolitica allowing a high-resolution understanding of the ecology, evolution and dissemination of these pathogens. However, to date no purpose-designed large-scale global population genomic analysis of Y. pseudotuberculosis has been performed. Here we present analyses of the genomes of 134 strains of Y. pseudotuberculosis isolated from around the world, from multiple ecosystems since the 1960s. Our data display a phylogeographic split within the populati

SUBMITTER: Seecharran T 

PROVIDER: S-EPMC5695210 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature