Clinical prediction rule for neurological sequelae due to acute encephalopathy: a medical community-based validation study in Harima, Japan.

ABSTRACT:

Objectives

This study aimed to verify the screening performance of our clinical prediction rule for neurological sequelae due to acute encephalopathy (NSAE-CPR), which previously identified the following three variables as predictive of poor outcomes: (1) refractory status epilepticus; (2) consciousness disturbance and/or hemiplegia at 6 hours from onset and (3) aspartate aminotransferase >90 IU/L within 6 hours of onset.

Design

Medical community-based multicentre retrospective cohort study.

Setting

Six regional hospitals in Harima and one tertiary centre in Kobe, Japan, from 2008 to 2012.

Participants

We enrolled a total of 1612 patients aged <16 years who met the diagnostic criteria for an initial diagnosis of complex febrile seizure. Patients with a history

SUBMITTER: Sasaki K 

PROVIDER: S-EPMC5695471 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature