Functional Connectivity Parcellation of the Human Thalamus by Independent Component Analysis.

ABSTRACT: As a key structure to relay and integrate information, the thalamus supports multiple cognitive and affective functions through the connectivity between its subnuclei and cortical and subcortical regions. Although extant studies have largely described thalamic regional functions in anatomical terms, evidence accumulates to suggest a more complex picture of subareal activities and connectivities of the thalamus. In this study, we aimed to parcellate the thalamus and examine whole-brain connectivity of its functional clusters. With resting state functional magnetic resonance imaging data from 96 adults, we used independent component analysis (ICA) to parcellate the thalamus into 10 components. On the basis of the independence assumption, ICA helps to identify how subclusters overlap spatiall

SUBMITTER: Zhang S 

PROVIDER: S-EPMC5695755 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature