Longitudinal fasting blood glucose patterns and arterial stiffness risk in a population without diabetes.

ABSTRACT:

Objective

To identify long-term fasting blood glucose trajectories and to assess the association between the trajectories and the risk of arterial stiffness in individuals without diabetes.

Methods

We enrolled 16,454 non-diabetic participants from Kailuan cohort. Fasting blood glucose concentrations were measured in 2006, 2008, and 2010 survey. Brachial-ankle pulse wave velocities were measured during 2011 to 2016. Multivariate regression model was used to estimate the difference of brachial-ankle pulse wave velocity levels and logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (95%CIs) of arterial stiffness risk, according to the fasting blood glucose trajectories.

Results

We identified five distinct fasting blood glucose traject

SUBMITTER: Wu Y 

PROVIDER: S-EPMC5695806 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature