Profiling of proteins secreted in the bovine oviduct reveals diverse functions of this luminal microenvironment.

ABSTRACT: The oviductal microenvironment is a site for key events that involve gamete maturation, fertilization and early embryo development. Secretions into the oviductal lumen by either the lining epithelium or by transudation of plasma constituents are known to contain elements conducive for reproductive success. Although previous studies have identified some of these factors involved in reproduction, knowledge of secreted proteins in the oviductal fluid remains rudimentary with limited definition of function even in extensively studied species like cattle. In this study, we used a shotgun proteomics approach followed by bioinformatics sequence prediction to identify secreted proteins present in the bovine oviductal fluid (ex vivo) and secretions from the bovine oviductal epithelial cells (in vit

SUBMITTER: Pillai VV 

PROVIDER: S-EPMC5695823 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature