Is Repeat Pulmonary Metastasectomy Indicated for Soft Tissue Sarcoma?

ABSTRACT: BACKGROUND:Because recurrence is high after pulmonary metastasectomy (PM) for soft tissue sarcoma (STS), repeat PM is commonly performed. Our objective was to define the selection criteria for repeat PM among patients experiencing recurrence and to identify factors associated with survival. METHODS:We reviewed a prospectively maintained database of 539 patients undergoing PM for STS. Characteristics of the primary tumor, metastatic disease, treatment, and recurrence were examined. Multivariable Cox models were constructed to identify factors associated with the likelihood of operative selection after recurrence. Overall survival between patients with or without repeat PM was estimated using the Kaplan-Meier method, with prognostic factors identified using Cox models. Both analyses incorpor

SUBMITTER: Chudgar NP 

PROVIDER: S-EPMC5696033 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature