Whole-lesion ADC histogram and texture analysis in predicting recurrence of cervical cancer treated with CCRT.

ABSTRACT:

Purpose

To explore the value of whole-lesion apparent diffusion coefficient (ADC) histogram and texture analysis in predicting tumor recurrence of advanced cervical cancer treated with concurrent chemo-radiotherapy (CCRT).

Methods

36 women with pathologically confirmed advanced cervical squamous carcinomas were enrolled in this prospective study. 3.0 T pelvic MR examinations including diffusion weighted imaging (b = 0, 800 s/mm²) were performed before CCRT (pre-CCRT) and at the end of 2nd week of CCRT (mid-CCRT). ADC histogram and texture features were derived from the whole volume of cervical cancers.

Results

With a mean follow-up of 25 months (range, 11 ∼ 43), 10/36 (27.8%) patients ended with recurrence. Pre-CCRT 75th, 90th, correlation, autocorrelation

SUBMITTER: Meng J 

PROVIDER: S-EPMC5696195 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature