Ontology highlight
ABSTRACT:
SUBMITTER: da Silva VL
PROVIDER: S-EPMC5696236 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Oncotarget 20171010 54
Cancer/testis (CT) genes are excellent candidates for cancer immunotherapies because of their restrict expression in normal tissues and the capacity to elicit an immune response when expressed in tumor cells. In this study, we provide a genome-wide screen for CT genes with the identification of 745 putative CT genes. Comparison with a set of known CT genes shows that 201 new CT genes were identified. Integration of gene expression and clinical data led us to identify dozens of CT genes associate ...[more]