Poor glycaemic control is associated with reduced exercise performance and oxygen economy during cardio-pulmonary exercise testing in people with type 1 diabetes.

ABSTRACT:

Background

To explore the impact of glycaemic control (HbA_1c) on functional capacity during cardio-pulmonary exercise testing in people with type 1 diabetes.

Methods

Sixty-four individuals with type 1 diabetes (age: 34 ± 8 years; 13 females, HbA_1c: 7.8 ± 1% (62 ± 13 mmol/mol), duration of diabetes: 17 ± 9 years) performed a cardio-pulmonary cycle ergometer exercise test until volitional exhaustion. Stepwise linear regression was used to explore relationships between HbA_1c and cardio-respiratory data with p ≤ 0.05. Furthermore, participants were divided into quartiles based on HbA_1c levels and cardio-respiratory data were analysed by one-way ANOVA. Multiple regression analysis was performed to explore the relationships between chang

SUBMITTER: Moser O 

PROVIDER: S-EPMC5697085 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature