Transcriptome sequencing and analysis of zinc-uptake-related genes in Trichophyton mentagrophytes.

ABSTRACT:

Background

Trichophyton mentagrophytes is an important zoonotic dermatophytic (ringworm) pathogen; causing severe skin infection in humans and other animals worldwide. Fortunately, commonly used fungal skin disease prevention and treatment measures are relatively simple. However, T. mentagrophytes is primarily studied at the epidemiology and drug efficacy research levels, yet current study has been unable to meet the needs of clinical medicine. Zinc is a crucial trace element for the growth and reproduction of fungi and other microorganisms. The metal ions coordinate within a variety of proteins to form zinc finger proteins, which perform many vital biological functions. Zinc transport regulatory networks have not been resolved in T. mentagrophytes. The T. mentagrophytes transcript

SUBMITTER: Zhang X 

PROVIDER: S-EPMC5697147 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature