Combined effects of leaks, respiratory system properties and upper airway patency on the performance of home ventilators: a bench study.

ABSTRACT:

Background

Combined effects of leaks, mechanical property of respiratory system and upper airway (UA) patency on patient-ventilator synchrony (PVA) and the level of clinically "tolerable" leaks are not well established in home ventilators.

Methods

We comparatively assessed on a bench model, the highest leak level tolerated without inducing significant asynchrony ("critical leak") in three home ventilators (Astral 150, Trilogy 100 and Vivo 60; noted as A150, T100 and V60 respectively) subjected to three simulated diseased respiratory conditions: chronic obstructive pulmonary disease (COPD), obesity hypoventilation (OHS) and neuromuscular disorders (NMD), with both open and closed UA. Also, total leak values in the device reports were compared to the bench-measured values.

SUBMITTER: Zhu K 

PROVIDER: S-EPMC5697337 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature