Genome-wide scans between two honeybee populations reveal putative signatures of human-mediated selection.

ABSTRACT: Human-mediated selection has left signatures in the genomes of many domesticated animals, including the European dark honeybee, Apis mellifera mellifera, which has been selected by apiculturists for centuries. Using whole-genome sequence information, we investigated selection signatures in spatially separated honeybee subpopulations (Switzerland, n = 39 and France, n = 17). Three different test statistics were calculated in windows of 2 kb (fixation index, cross-population extended haplotype homozygosity and cross-population composite likelihood ratio) and combined into a recently developed composite selection score. Applying a stringent false discovery rate of 0.01, we identified six significant selective sweeps distributed across five chromosomes covering eight genes. These genes are ass

SUBMITTER: Parejo M 

PROVIDER: S-EPMC5697678 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature