On the Use of Summary Comorbidity Measures for Prognosis and Survival Treatment Effect Estimation.

ABSTRACT: Prognostic scores have been proposed as outcome based confounder adjustment scores akin to propensity scores. However, prognostic scores have not been widely used in the substantive literature. Instead, comorbidity scores, which are limited versions of prognostic scores, have been used extensively by clinical and health services researchers. A comorbidity is an existing disease an individual has in addition to a primary condition of interest, such as cancer. Comorbidity scores are used to reduce the dimension of a vector of comorbidity variables into a single scalar variable. Such scores are often added to regression models with other non-comorbidity variables such as age and sex, both for analyzing prognosis and for confounder adjustment when analyzing treatment effects. Despite their wid

SUBMITTER: Gilbert EA 

PROVIDER: S-EPMC5697800 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature