Effects of spatial smoothing on functional brain networks.

ABSTRACT: Graph-theoretical methods have rapidly become a standard tool in studies of the structure and function of the human brain. Whereas the structural connectome can be fairly straightforwardly mapped onto a complex network, there are more degrees of freedom in constructing networks that represent functional connections between brain areas. For functional magnetic resonance imaging (fMRI) data, such networks are typically built by aggregating the blood-oxygen-level dependent signal time series of voxels into larger entities (such as Regions of Interest in some brain atlas) and determining their connection strengths from some measure of time-series correlations. Although it is evident that the outcome must be affected by how the voxel-level time series are treated at the preprocessing stage, the

SUBMITTER: Alakorkko T 

PROVIDER: S-EPMC5698731 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature