Detection of generalized tonic-clonic seizures using surface electromyographic monitoring.

ABSTRACT:

Objective

A prospective multicenter phase III trial was undertaken to evaluate the performance and tolerability in the epilepsy monitoring unit (EMU) of an investigational wearable surface electromyographic (sEMG) monitoring system for the detection of generalized tonic-clonic seizures (GTCSs).

Methods

One hundred ninety-nine patients with a history of GTCSs who were admitted to the EMU in 11 level IV epilepsy centers for clinically indicated video-electroencephalographic monitoring also received sEMG monitoring with a wearable device that was worn on the arm over the biceps muscle. All recorded sEMG data were processed at a central site using a previously developed detection algorithm. Detected GTCSs were compared to events verified by a majority of three expert reviewers.<

SUBMITTER: Halford JJ 

PROVIDER: S-EPMC5698770 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature