ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR.

ABSTRACT:

Background

Dyslexia is a specific learning disorder affecting reading and spelling abilities. Its prevalence is ~5% in German-speaking individuals. Although the etiology of dyslexia largely remains to be determined, comprehensive evidence supports deficient phonological processing as a major contributing factor. An important prerequisite for phonological processing is auditory discrimination and, thus, essential for acquiring reading and spelling skills. The event-related potential Mismatch Response (MMR) is an indicator for auditory discrimination capabilities with dyslexics showing an altered late component of MMR in response to auditory input.

Methods

In this study, we comprehensively analyzed associations of dyslexia-specific late MMRs with genetic variants previously re

SUBMITTER: Muller B 

PROVIDER: S-EPMC5698869 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature